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On Host - Parasite Relations.






mosquitoPaul Gosselin (June 2004)

In Canada hordes of mosquitoes, black flies and horse flies which, in the summer, take turns making life out of doors difficult, if not miserable. In the far north, the situation can be worse than unpleasant as Davidson and Rugg, in The Complete Wilderness Paddler (1975/83 Vintage Books New York) attest:

From a Christian or creationist point of view one might envisage the question "Is God some sort of sadist taking pleasure in inventing convoluted torments for his children ??" If not, then why create such irritating and perverse critters ??



Explanation

The american geneticist Kevin Anderson notes (2004): "Parasitic bacteria can fairly easily be understood in terms of "loss of function." As the ability of the organism became genetically depleted, it was forced to depend upon other biological systems to greater and greater degree, until it finally became fully parasitic, hence pathogenic to the host. Such transformation may apply to non-microorganisms also."


Potential to pharmaceuticals:
If we take the mosquito for example, it is known to inject an anticoagulant substance before beginning to extract the host's blood. If we look at the present host - mosquito relationship in the perspective that it was formerly symbiotic, then there is a possibility that one of the substances injected would have been beneficial to it's host. Perhaps the anticoagulant or perhaps some other unknown substance. There is then the possibility that an unknown substance injected by the mosquito (perhaps the anticoagulant isn't the only substance injected) may be of some use to men. As an example, an article by Matt Kaplan, in the July issue of New Scientist explores how certain parastic worms could be used as therapy to combat allergies in humans.


Pitfalls and Traps for this line of inquiry.
le ver plat
flat worm
(Tœnia solium)
There are plentyof traps to fall into however in following such a line of thought. On has to consider that not all present host - parasite relationships may represent former symbiotic relationships. That is, before the Fall mosquitos may not have targetted humans, in which case searching for substances beneficial to humans in mosquitoes may be futile. In other cases there may be a possibility (from a biblical perspective) of determining if there was a previous symbiotic relationship or not. For example, in the case of worms picked up by humans after eating unproperly cooked pork. We don't even have to back up to the Fall to figure out this one as the Bible tells us that predator - prey relations appeared after the Flood (Man became a predator -> Gen. 9: 2-4). From biblical information then, we would know that these worms, picked up by humans eating pork, introduced an unintended relationship. We could then establish that this particular predator - prey relationship is then accidental (unintented in the original creation) and so looking for beneficial substances for humans in the pork worms is futile. These worms, however, may have been formerly beneficial to herbivores (such as pigs or sheep). One may also speculate that before the Flood one of the forms of wickedness found among the antedeluvials may have been bestiality, which would have introduced parasitic organisms to hosts they were never supposed to encounter. This in turn would explain in part the forbidding of sex between humans and other species[1] in Leviticus 20: 15.

Another line of thought about pitfalls for this type of research is that even if we have identified a proper parasite - host relationship (previously symbiotic[2]), parasitic organisms, being fallen creatures too, the substances presently injected will not necessarily be identical to those formerly injected (by the mosquito for example). One would have to start by doing an inventory of the various substances presently injected and then look for chemical "cousins" (perhaps larger molecules or molecules related in some way to those presently found ?) in order to find the original beneficial substance. I would not expect discovering beneficial substances this way to be a easy process. There may be too many changes in the vector organism (presently a parasite) itself (metabolism, chemical processes, etc.) and it's relations with other organisms to enable us to identify the original beneficial substances. There is an additional problem. The host organism's metabolism may no longer be capable of using the original beneficial substance (even if we did manage to find it). Nonetheless, creationist pharmaceutical researchers may well find this perspective useful in exploring our world for new medecines for humans or for veterinary purposes. Perhaps someone will "get lucky".

Further speculations
Reflecting on symbiotic relations in an unfallen world, the creationist David Bump throws out the following ideas:

Jonathan Bartlett adds:

After the original Creation, Genesis seems to mention genetic changes to living organisms on two occasions (though another possiblity is switching on dormant genes deep in the so-called "junk DNA"). Once at the Fall itself (thorns are mentioned as new) and also immediately after the Flood when "carnivory" (eating meat) is mentioned for the first time as well as the fact that animals would now fear humans from then on (Gen 9: 2-3). This implies that there was no such thing as a "wild animal" before the Flood. It is also implied by prophets discussing the restoration of all things that predation is actually an abnormal state of affairs, which will eventually be put an end to when things will be returned to their normal state in Messianic Times:

But let's get back to "carnivory" after the Flood. One hypothesis I've heard is that certain plant foods available before the Flood became extinct and thus many organisms had to become carnivores to get their allotment of protein. On the other hand, perhaps carnivory was not due to species of plants going extinct, but rather ecosystems disappearing. For example, in our world Clover lives in a symbiotic relation with a particular bacteria species (called Bacillus radicicola) which produces nitrogen which clover needs. Now suppose that the bacteria had a genetic modification, which no longer enabled it to produce a certain enzyme essential to its relation with clover. Perhaps clover and the bacteria would still exist, but repercussions to the biosphere would still be important nevertheless...

Perhaps after the Flood similar symbiotic inter-species relationships as well as ecosystems were destroyed, and as a result many animals had to change their feeding habits. When this change occurred, they were not necessarily genetically modified, but perhaps this environmental change was a trigger to switch on what evolutionists still call "Junk DNA" allowing these animals (now carnivores) to adapt to this new situation and perhaps switch on a "new" phenotype (that is, not previously observed).


Post-Scriptum: On reading this note a friend of mine with a background in mircobiology and doing cardic research commented that one would have to have some explanation for immunological systems in humans (and other organisms) as basically what I'm saying here is that originally there wouldn't have been any need for immunological systems at all as everything would have been perfect to begin with. While it is quite true that from a Biblical point of view everything would have been perfect to begin with, I think it is quite logical to assume that in the same way that the Creator had foreseen the possibility of the Fall and already thought of the possibility of our needing a Savior, He had also foreseen the physical consequences of the Fall and provided organisms with immunological systems "just in case". In engineering terms this is called "overdesign" and provides a mechanism with back-up systems in case of "unforseen" problems. I don't think this requires any further explanation.

wasp & parasite
the wasp and its parasite


Notes

[1] - Though there may be reasons other than biological for this prohibition.

[2]- Ex. Supposing the mosquito's original target was indeed humans.

Kaplan, Matt (2009) Just what the doctor ordered? pp. 42-45 New Scientist 11 July vol. 203 no. 2716